Vaccine reactivity has been linked to a temporary increase in inflammatory cytokines that act on blood vessels, muscles, and other tissues. Acta Neurol Belg. Centers for Disease Control and Prevention. According to reports, these complications are more common in men and women between the ages of 20 and 60 [9]. Repajic M, Lai XL, Xu P, Liu A. Bells Palsy after second dose of Pfizer COVID-19 vaccination in a patient with history of recurrent Bells palsy. For example, if you fear getting the vaccine because you might have an allergic reaction, consult the facts: one study of the Pfizer vaccin e showed . Woo CJ, Chou OHI, Cheung BMY. Research suggests that between one month and one year after having COVID-19, 1 in 5 people ages 18 to 64 has at least one medical condition that might be due to COVID-19. They signal that your immune system is responding to the shot and building up protection against the coronavirus. Accessed May 24, 2022. Fewer people should get sick, and more lives can be saved. In December 2019, the SARS Covid-2 virus was introduced to the world. And a recent study found that 30% of people who had Covid-19 still had symptoms up . COVID-19 vaccines for kids: What you need to know, COVID-19 vs. flu: Similarities and differences. There was a recent report of Ramsey Hunt Syndrome (RHS after the Pfizer vaccination. Med J Aust 2011;194:168. Google Scholar. fever or chills. These effects are often acute and transient, but they can be severe and even fatal in a few cases. New Engl J Med. If you have never had COVID-19, you may notice more side effects after the second dose than after the first dose. Many. But the side effect. Pulmonary embolism, transient ischaemic attack and thrombocytopenia after the Johnson & Johnson COVID-19 vaccine. Coronavirus disease 2019 and cardiovascular complications: Focused clinical review. Watad A, De Marco G, Mahajna H, Druyan A, Eltity M, Hijazi N, Haddad A, Elias M, Zisman D, Naffaa ME. Chills. Sect. Immunization stress-related response: a manual for program managers and health professionals to prevent, identify and respond to stress related responses following immunization. ** CDC provided recommendations on who should be vaccinated first because COVID-19 vaccine supply was initially limited. As of November 2022, 630.3 million people have been diagnosed with COVID-19 and 6.58 million deaths worldwide, according to WHO figures [2]. 2021. https://doi.org/10.6061/clinics/2021/e3286. The CDC noted that the two mRNA vaccines, from Pfizer and Moderna, are preferred over the Johnson & Johnson vaccine, which remains available for those who prefer it and for use in certain circumstances. Syncopal events after influenza vaccination were reported most frequently among persons aged 1829 years; the median patient age was 26 years (range=1888 years). 2021;42(9): e1213. 2014;13(3):21524. Amyotrophic neuralgia secondary to Vaxzevria (AstraZeneca) COVID-19 vaccine. More common side effects are mild and temporary, including: fever. Researchers have used the body's own immune cells to develop a nano-vaccine against Covid-19, according to a new study conducted in mice. Schulz JB, Berlit P, Diener HC, Gerloff C, Greinacher A, Klein C, Petzold GC, Piccininni M, Poli S, Rhrig R. COVID-19 vaccine-associated cerebral venous thrombosis in Germany. Approximately one quarter of the syncopal and other anxiety-related events after receipt of Janssen COVID-19 vaccine described in this report occurred in persons who reported a history of similar events after vaccination. 2021;358: 577606. Hosseini, R., Askari, N. A review of neurological side effects of COVID-19 vaccination. Another CDC report released Friday looked at side effects reported by more than 300,000 J&J vaccine recipients. Franchini M, Testa S, Pezzo M, Glingani C, Caruso B, Terenziani I, Pognani C, Bellometti SA, Castelli G. Cerebral venous thrombosis and thrombocytopenia post-COVID-19 vaccination. 2021; doi:10.1097/HJH.0000000000002819. Vaccines based on mRNA and adenovirus have been reported to be most likely to cause headaches [26]. Syncope and other anxiety-related events can occur after vaccination and have been reported to the Vaccine Adverse Events Reporting System (VAERS) for other vaccines. PubMedGoogle Scholar. loss of smell. A MedDRA coded event does not indicate a medically confirmed diagnosis. Your Side Effects Don't Go Away iStock If any of the "normal" side effectsincluding pain, redness or swelling in the injection area or fatigue, headache, muscle pain, chills, fever, nauseadon't seem to go away after a few days, you should call your doctor ASAP. 2021;74(708):2736. 2021;208: 106887. Local Side Effects You may experience pain, redness, and swelling where you got the shot. 2021. https://doi.org/10.1007/s00415-021-10780-7. Adenovirus-based vaccines are at the forefront of causing this complication due to the transfer of the nucleic acids encoding the viral spike (S) protein. If you receive a J&J vaccine, for three weeks, you should watch for possible symptoms of TTS and get medical help immediately if you have any of these symptoms: According to the CDC, anyone who has a known severe allergy (e.g., anaphylaxis) to any of the vaccine ingredients should not receive that vaccine. They signal that your immune system is responding to the shot and building up protection against the coronavirus. PubMed Second, because the Janssen vaccine is under EUA and health care providers are required to report potentially life-threatening events, a reporting bias might exist. You might have other tests or procedures, such as chest X-rays, based on your symptoms. Al-Mashdali AF, Ata YM, Sadik N. Post-COVID-19 vaccine acute hyperactive encephalopathy with dramatic response to methylprednisolone: a case report. First, VAERS is a passive surveillance reporting system and subject to underreporting (1). However, anyone who gets COVID-19 can have long-term effects, including people with no symptoms or mild illness with COVID-19. ori L, Rajovi-Mrki I, olak E, Miri D, Kisi B. Sputnik-V reactogenicity and immunogenicity in the blood and mucosa: a prospective cohort study. By comparison, after influenza vaccination, the reporting rate of syncope was 0.05 episodes per 100,000 doses. Among the 653 VAERS reports of syncope, 327 (50%) occurred in women. In fact, the viral antigens of the vaccine stimulate an immunological response in the spinal cord [62]. Over the couple of days she developed severe . According to the vaccine study literature, adverse effects have always been part of the mass vaccination strategy, but ultimately the desired effects of the vaccination are more significant. Cureus. The reporting rates of syncope to VAERS after Janssen COVID-19 and influenza vaccines (201920) were 8.2 and 0.05 per 100,000 doses, respectively. Some symptoms are similar to those caused by chronic fatigue syndrome and other chronic illnesses that develop after infections. Bjrnstad-Tuveng TH, Rudjord A, Anker P. Fatal cerebral haemorrhage after COVID-19 vaccine. In some people, post-COVID-19 syndrome lasts months or years or causes disability. Lancet Infect Dis. Vogrig A, Janes F, Gigli GL, Curcio F, Del Negro I, DAgostini S, Fabris M, Valente M. Acute disseminated encephalomyelitis after SARS-CoV-2 vaccination. Recommendations for observation after COVID-19 vaccine administration are available at https://www.cdc.gov/vaccines/covid-19/info-by-product/clinical-considerations.html. MMWR Morb Mortal Wkly Rep 2021;70:6516. "We don't know why that is, how long these symptoms will last or if there are effective ways to treat them. The Lancet. Finally, the Janssen COVID-19 vaccine was not directly compared with other currently available COVID-19 vaccines and instead was compared with influenza vaccine administered during the 201920 season. Dutta S, Kaur R, Charan J, Bhardwaj P, Ambwani SR, Babu S, Goyal JP, Haque M. Analysis of neurological adverse events reported in VigiBase from COVID-19 vaccines. * Each VAERS report might be assigned more than one MedDRA preferred term. 2021;121: 102662. Liu BD, Ugolini C, Jha P. Two cases of post-Moderna COVID-19 vaccine encephalopathy associated with nonconvulsive status epilepticus. Hasan T, Khan M, Khan F, Hamza G. Case of Guillain-Barr syndrome following COVID-19 vaccine. panic attacks after vaccine. Ann Emergency Med. People with severe symptoms of COVID-19 often need to be treated in a hospital intensive care unit. The Pfizer-BioNTech Covid-19 vaccine is associated with an increased risk of myocarditis, an inflammation of the heart muscle, a large new study from Israel confirms. Covid also seems to have a stronger effect on people's neurological and mental health than other respiratory conditions: In the new study, there was overall a 44% greater risk of neurological . now i keep having panic attacks, even though i'm not panicking about anything. 2021;21(5): e535. Clin Neurol Neurosurg. Khan E, Shrestha AK, Colantonio MA, Liberio RN, Sriwastava S. Acute transverse myelitis following SARS-CoV-2 vaccination: a case report and review of literature. How well do face masks protect against COVID-19? Cookies used to make website functionality more relevant to you. Saeed S, et al. An overview of current COVID-19 vaccine platforms. Syncope, a common anxiety-related event reported by the five mass vaccination sites, has specific MedDRA preferred terms (syncope and syncope vasovagal) and was the focus of this follow-up investigation. VAERS reports are limited by the information provided by the reporter and might be incomplete, although those missing information regarding the time of vaccination or the time of the event were not included. Overall, the benefits of being vaccinated are much greater than the risks involved. The anxiety-related events described here were reported before reports of thrombosis with thrombocytopenia syndrome (7). Garca-Azorn D, Do TP, Gantenbein AR, Hansen JM, Souza MNP, Obermann M, Pohl H, Schankin CJ, Schytz HW, Sinclair A. 241(d); 5 U.S.C. 2021. https://doi.org/10.1007/s12024-021-00440-7. Four of the five sites temporarily closed while an investigation took place. 2021;14(6): e243629. 2022;269(1):558. J Neuroimmunol. part 46, 21 C.F.R. The National Alliance on Mental Health suggest . Herpes zoster following COVID-19 vaccine: a report of three cases. 2022. https://doi.org/10.1136/postgradmedj-2021-141022. https://covid19.who.int/mapFilter=deaths. CDC twenty four seven. Those with a history of severe allergic reaction (anaphylaxis) to injectables or other vaccines should discuss the vaccination with their doctor, who can evaluate and assess their risk. Thank you for taking the time to confirm your preferences. A panic attack is defined as a sudden rush of intense feelings that can include a racing or pounding heart, trembling, sweating, shallow breathing, chest pain, a fear of choking, nausea, dizziness, and a fear of losing it or going crazy or even of imminent death. All authors have completed and submitted the International Committee of Medical Journal Editors form for disclosure of potential conflicts of interest. Following the COVID-19 virus epidemic, extensive, coordinated international research has led to the rapid development of effective vaccines. After getting vaccinated for COVID-19, you might experience some temporary symptoms similar to those you might notice when you get a flu shot, such as a sore, swollen arm where you got the shot. Many have suffered chronic fatigue, chest pain, shortness of breath and brain fog months after their infection. Early outcomes of bivalirudin therapy for thrombotic thrombocytopenia and cerebral venous sinus thrombosis after Ad26. 2021;90(4):62739. Had COVID back in December during Christmas. In addition to the anxiety-related events reported by the five mass vaccination sites, review of all VAERS reports containing the MedDRA term syncope or syncope vasovagal after vaccination with Janssen COVID-19 vaccine during March 2April 11 identified 653 eligible reports (reports missing information regarding time of vaccine receipt and event were not included) (Table 2). Watch out for neuromyelitis optica spectrum disorder after inactivated virus vaccination for COVID-19. 2021;397(10269):99111. QJM: An Int J Med. Syncopal events that occurred off-site or 1 hour after vaccine administration and those in 16 persons who received diphenhydramine or epinephrine were not included. Cookies policy. Sore throat Congestion/runny nose Loss of smell or taste Nausea Diarrhea The virus can lead to pneumonia, respiratory failure, heart problems, liver problems, septic shock, and death. Ann Med Surg. S Vaccine. 3501 et seq. Ann Neurol. Due to the activity of the immune system, after the injection of COVID-19 vaccines, especially adenovirus-based type, thrombocytopenia, cerebral venous sinus thrombosis, ischemic stroke and intracerebral hemorrhage, have also been reported [27]. Who Had Serious Side Effects from Covid 19 Vaccine? Because the Janssen COVID-19 vaccine is administered as a single dose, this vaccine might be a more attractive option for persons who have needle aversion. https://www.cdc.gov/mis/index.html. Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK. Google Scholar. 2021;12:20837. Anxiety, panic attacks, and COVID-19 can share symptoms, including chills and shortness of breath. More generally, the majority of demyelinating syndromes are related to mRNA-based vaccines, followed by adenovirus-based vaccines. 2021;69(9):2550. RHS leads to facial nerve palsy, vestibulocochlear neuropathy, and glossopharyngeal nerve neuropathy, so it causes numbness of the face, tongue, and hearing loss. Top Magn Reson Imaging. Parrino D, Frosolini A, Gallo C, De Siati RD, Spinato G, de Filippis C. Tinnitus following COVID-19 vaccination: report of three cases. Side-effects with the COVID-19 vaccines are never pleasant and the hesitancy of developing the reactions have scared many into getting jabbed. Delayed headache after COVID-19 vaccination: a red flag for vaccine induced cerebral venous thrombosis. The most important and most common complications are cerebral venous sinus thrombosis (more about AstraZeneca), transverse myelitis (more about Pfizer, Moderna, AstraZeneca, and Johnson & Johnson), Bell's palsy (more about Pfizer, Moderna, AstraZeneca), GBS (more about Pfizer, AstraZeneca, and Johnson & Johnson), and the first manifestation of MS (more about Pfizer). Investigators note that people with this syndrome tend to experience increased post-traumatic stress, general stress, anxiety, health anxiety, and suicidal ideation. The most common symptoms of long COVID are: extreme tiredness (fatigue) shortness of breath. Getting the COVID-19 vaccine offers you ample protection against the virus but can also cause a few non-serious side effects such as fatigue, soreness at the injection site, nausea, chills, or a . Department of Health and Human Services. Delayed swelling, redness or a rash at the injection site. Comput Struct Biotechnol J. #BestPractices. Abbreviations: N = no; Y=yes. The COVID-19 vaccine-related convulsions can be attributed to the synthesis and release of spike proteins, which cause severe inflammation and hyperthermia. Finsterer J. Bells palsy following COVID-19 vaccination: a case report. In clinical trials, two participants in their . Multisystem inflammatory syndrome (MIS). The majority -- 61% -- were women, the median age was 36 years and 20% of the patients told vaccination site staff they had a history of fainting associated with receiving injections or an aversion to needles. The findings in this report are subject to at least three limitations. Herpes zoster is a disease that occurs as a result of the reactivation of the varicella-zoster virus (VZV) after receiving the COVID-19 vaccine. AskMayoExpert. endorsement of these organizations or their programs by CDC or the U.S.
This was because the population that received Janssen vaccine during its introduction differed from that of the mRNA COVID-19 vaccines because of the prioritization (e.g., by age group, occupation, or underlying health condition) of COVID-19 vaccines. These ongoing health problems are sometimes called post-COVID-19 syndrome, post-COVID conditions, long COVID-19, long-haul COVID-19, and post acute sequelae of SARS COV-2 infection (PASC). Sect. Signs and symptoms in VAERS reports are coded using the Medical Dictionary for Regulatory Activities (MedDRA) preferred terms. Post-COVID-19 syndrome. Each of the five sites reported all anxiety-related events to VAERS; reports for each event were reviewed by CDC. 2021;19:250817. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). The median age of persons with syncope after Janssen COVID-19 vaccination was 30 years (range=1882 years). Bourguignon A, Arnold DM, Warkentin TE, Smith JW, Pannu T, Shrum JM, Al Maqrashi ZA, Shroff A, Lessard M-C, Blais N. Adjunct immune globulin for vaccine-induced immune thrombotic thrombocytopenia. Google Scholar. The vaccine cannot cause a COVID-19 infection, so symptoms mean your body is building a healthy immune response. Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. Garg RK, Paliwal VK. nausea and vomiting. 2021;42(11):43979. 2021;21(4):4502. Iba T, Levy JH, Warkentin TE. Recognizing vaccine-induced immune thrombotic thrombocytopenia. We take your privacy seriously. 2021;202:1823. Considering the hundreds of millions of COVID-19 vaccine doses that have been administered, these reports are very rare. Romn GC, Gracia F, Torres A, Palacios A, Gracia K, Harris D. Acute transverse myelitis (ATM): clinical review of 43 patients with COVID-19-associated ATM and 3 post-vaccination ATM serious adverse events with the ChAdOx1 nCoV-19 vaccine (AZD1222). For all four vaccines, pain at the injection. https://www.cdc.gov/coronavirus/2019-ncov/long-term-effects.html. Reporting rates were calculated using the approximate number of doses of each vaccine administered during the respective analysis periods. Descriptive analyses of VAERS data were stratified by vaccine type, sex, and age group. Zhang Y, Zeng G, Pan H, Li C, Hu Y, Chu K, Han W, Chen Z, Tang R, Yin W. Safety, tolerability, and immunogenicity of an inactivated SARS-CoV-2 vaccine in healthy adults aged 1859 years: a randomised, double-blind, placebo-controlled, phase 1/2 clinical trial. To prepare for your appointment, write down: Your health care provider might do lab tests, such as a complete blood count or liver function test. Due to the leakage of these genetic materials and their binding to factor 4 platelet, autoimmunity develops [29]. Adverse reactions after the second dose of the vaccine are reported more than in the first dose [5]. 42(45):36675. In America, there are still a lot of people not willing to get vaccinated. Thromb Res. Ramdeny S, Lang A, Al-Izzi S, Hung A, Anwar I, Kumar P. Management of a patient with a rare congenital limb malformation syndrome after SARS-CoV-2 vaccine-induced thrombosis and thrombocytopenia (VITT). 2022;362: 577765. Ozgen Kenangil G, Ari BC, Guler C, Demir MK. Median patient age was 36 years (range=1877 years). The Food and Drug Administration warned on Monday that Johnson & Johnson's coronavirus vaccine can lead to an increased risk of a rare neurological condition known as Guillain-Barr syndrome . Reported side effects of COVID-19 vaccines have mostly been mild to moderate and have lasted no longer thana few days. 2021. https://doi.org/10.4045/tidsskr.21.0312. https://doi.org/10.1186/s40001-023-00992-0, DOI: https://doi.org/10.1186/s40001-023-00992-0. Most people have a sore arm right after being vaccinated, and more body-wide effects like fever and chills within 8 to 12 hours. Salinas MR, Dieppa M. Transient akathisia after the SARS-Cov-2 vaccine. Crit Care Med. The process that causes the disorder is probably explained by the fact that the varicella-zoster virus CD8+killer cells, after vaccination, are temporarily unable to control VZV due to the extensive change of simple CD8+cells to the COVID-19 virus CD8+killer cells. 2021;25(5):3023. These symptoms do not mean you are sick. Centers for Disease Control and Prevention. COVID-19 vaccine-induced encephalitis and status epilepticus. It isn't clear how long these effects might last. Obermann M, Krasniqi M, Ewers N, Fayad J, Haeberle U. Bells palsy following COVID-19 vaccination with high CSF antibody response. The two main mechanisms, ectopic immune reactions, and molecular mimicry, have been proposed for the pathogenicity of vaccines and how these complications occur. Mikkelsen ME, et al. In addition, in mass vaccination situations, an anxiety-related event witnessed by others on-site or reported through media coverage might provoke additional anxiety-induced episodes (4). Its helpful to understand side effects before you get a COVID-19 vaccine. CDC interviewed staff members from the five mass COVID-19 vaccination sites that reported anxiety-related adverse event clusters after receipt of Janssen COVID-19 vaccine, focusing on site capacity and layout, vaccination processes, timeline of reported events, and clinical follow-up. Events that occurred off-site or 1 hour after vaccine administration and those in persons who received diphenhydramine or epinephrine at the vaccination visit were not included. Cases per 100,000 persons vaccinated. CAS In early 2021, the first vaccines were introduced to stop the pandemic. Anyone you share the following link with will be able to read this content: Sorry, a shareable link is not currently available for this article. It is necessary to pay attention to the fact that in mass vaccination, due to different races, disease history, age, lifestyle, and other effective factors, the incidence of adverse effects of vaccination is higher. 2021. https://doi.org/10.1016/j.nrleng.2021.05.002. 2021;9(5):435. Article Int Forum Allergy Rhinol. i had been worried about it beforehand but not to the point where i had an attack. Int J Audiol. Post-COVID conditions: Overview for healthcare providers. We are vaccinating all eligible patients. Herein, we have provided a comprehensive review of documents reporting neurological side effects of COVID-19 vaccines in international databases from 2020 to 2022 and discussed neurological disorders possibly caused by vaccination. Cite this article. Complications usually appear within one day to 1month after injection and are usually acute, transient, and self-limiting, but in severe cases lead to hospitalization and intensive care [8]. Article Keywords used for this search included COVID-19, SARS-CoV-2, vaccination, side effects, complications, vascular thrombosis, thrombocytopenia, myelitis, demyelination, and all kind of mRNA vaccines, Adenovirus vaccine, Pfizer, AstraZeneca, Johnson & Johnson, Moderna, Sinovac, Sinopharm, Sputnik, and Covaxin. ), or your upcoming vacation. Transverse myelitis is an inflammation of a part of the spinal cord that usually occurs after infection and is associated with impaired sensory, motor, and autonomic function (bladder and intestines) in areas below the area of inflammation in the spinal cord. Efficacy and side effects of Sputnik V, Sinopharm and AstraZeneca vaccines to stop COVID-19; a review and discussion. This content does not have an English version. Another CDC report released Friday looked at side effects reported by more than 300,000 J&J vaccine recipients. Anne M. Hause, PhD1; Julianne Gee, MPH1; Tara Johnson, MPH, MS1; Amelia Jazwa, MSPH1; Paige Marquez, MSPH1; Elaine Miller, MPH1; John Su, MD, PhD1; Tom T. Shimabukuro, MD1; David K. Shay, MD1 (View author affiliations). Data show that the vaccines are very good at preventing serious or deadly cases of COVID-19 even after considerable time since completing vaccination. 31 On the contrary, people in poor and developing countries, including health workers, have not received full COVID-19 immunization. PubMed Central Sect. According to a recent report on the Sputnik vaccine, side effects are included headache, joint pain, fever, and flu-like symptoms [14]. 13 days after the moderna vaccine (3/15) I began to have dizzy spells and panic attacks at work. Six persons who received diphenhydramine or epinephrine at the vaccination visit were excluded because these events might have represented allergic reactions; none was classified as anaphylaxis. The stress of an ongoing pandemic might also increase anxiety surrounding COVID-19 vaccination. Chills and swollen lymph nodes can also occur. Angana Chakrabarti 25 July, 2021 12:01 pm IST Etemadifar M, Sigari AA, Sedaghat N, Salari M, Nouri H. Acute relapse and poor immunization following COVID-19 vaccination in a rituximab-treated multiple sclerosis patient. At a Glance People can develop shingles after COVID-19 vaccination, but it's rare. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Correspondence to Alpalho M, Filipe P. Herpes Zoster following SARS-CoV-2 vaccinationa series of four cases. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. These symptoms are part of the body's natural 'fight, flight, or freeze' response. Possible side effects: Pain, redness, or swelling at the site where the shot was administered, and/or tiredness, headache, muscle pain, chills, fever, or nausea throughout the rest of the body. Introna A, Caputo F, Santoro C, Guerra T, Ucci M, Mezzapesa DM, Trojano M. Guillain-Barr syndrome after AstraZeneca COVID-19-vaccination: a causal or casual association? Multisystem inflammatory syndrome in children (MIS-C), Safe outdoor activities during the COVID-19 pandemic, Safety tips for attending school during COVID-19, Advertising and sponsorship opportunities, Symptoms that get worse after physical or mental effort, Lung (respiratory) symptoms, including difficulty breathing or shortness of breath and cough, Neurological symptoms or mental health conditions, including difficulty thinking or concentrating, headache, sleep problems, dizziness when you stand, pins-and-needles feeling, loss of smell or taste, and depression or anxiety, Heart symptoms or conditions, including chest pain and fast or pounding heartbeat, Digestive symptoms, including diarrhea and stomach pain, Blood clots and blood vessel (vascular) issues, including a blood clot that travels to the lungs from deep veins in the legs and blocks blood flow to the lungs (pulmonary embolism), Other symptoms, such as a rash and changes in the menstrual cycle, You had certain medical conditions before getting the, You had a condition affecting your organs and tissues (multisystem inflammatory syndrome) while sick with. Focus on anything other than the needle stick: a spot on the floor, the positive effects of getting a COVID-19 vaccine (soon you can hug your family! Sharifian-Dorche M, Bahmanyar M, Sharifian-Dorche A, Mohammadi P, Nomovi M, Mowla A. Vaccine-induced immune thrombotic thrombocytopenia and cerebral venous sinus thrombosis post COVID-19 vaccination; a systematic review. During March and April 2021, among 7.98 million doses of Janssen COVID-19 vaccine administered in the United States, the VAERS reporting rate of syncope after Janssen COVID-19 vaccination was 8.2 per 100,000 doses. n R, truncov D. Status epilepticus as a complication after COVID-19 mRNA-1273 vaccine: a case report.