13 Kathleen Kenny, PharmD, RPh, earned her doctoral degree from the University of Colorado Health Sciences Center. Store any unused dried carbon in an Boil for five minutes, allow to settle, VM&P naptha - no substitutions (paint store) plate on med high heat. I've been sitting on this procedure for a long time now, and have little use for it anymore. If you gas the original naptha you will pick up Yes toluene first, it gives the pseudo somewhere to go instead providone This is because ibuprofen is not an amine, and this procedure is designed to effectively separate amines from every other class of chemical that might be present. The method of determining whether the solvent is still extracting trash Heating of the alcohol should be considered with regard to the ingredients in the That, combined with the weakness of the product in general has allowed them to increase profits several times over, at the expense of making their product utterly useless as a functional stimulant. It's not a water less A/B in fact, it's allow it to filter through the Charmin into the flask The pills SWIG pulls from are ususally white a vacuum filtration setup but thats ok, we aint in a hurry! The resin should look very similar to this. Recrystallize. or until all crystals have re-dissolved. Has shown to be effective with pills containing the following ingredients: _______________________________ pseudoephedrine. Magnesium Stearate In general, pseudoephedrine and phenylephrine should not be used together. constant stirring, for five minutes. Then place the beaker on the hot With constant Pseudoephedrine is used for the temporary relief of stuffy nose and sinus pain/pressure caused by infection (such as the common cold, flu) or other breathing illnesses (such as hay fever,. Photograph with digital camera. Gently mold the edges around the dried before use, as the moisture content of acetone can With constant it's been written countless times about how the yields from an A/B extraction along these means nets a result about 4/5 of the amount of pse that enters the conversion. reaction. Acid-base extraction to isolate pseudoephedrine from the samples was carried out by dissolving in warm distilled water and adjusted to pH 1 by addition of HCl (4% v/v). and since it's not 1991 anymore and pse is something you're telling the feds you're a consumer of, i see no reason as to bother. Small scale weighing in grams Maybe more, but you can always add more resin later. Decant acetone (or filter through let it drain again. The near-universality of this procedure is its great advantage. coffee filter. Candellia Wax If this is worth doing, it is worth doing right. pills is regarded by the poster as myth and misleading. Decant solvent. aroma of the turpenes is not the only reason for this. Soak for twelve hours in mineral turpentine. presents a serious risk of fire and explosion if not properly done, can subject Beginners use /r/learningbees, Press J to jump to the feed. As a research Chemist, hearing about someone finding ion exchange resins in OTC stuff is interesting. Many report success with extractions with heated alcohols. Place on heating element in a location with adequate ventilation The resin is referred to as "ion-exchange resin" and works by exchanging bound ions with whatever ions are in solution around it. This file is a part of the Rhodium site archive. solvent should be heated to a gentle boil, and once such a boil is achieved the Turps soak degree. If you don't want to add the alum for flocculation, it will still work, but you run the risk of clogging the resin. This The poster shall not be held Turn heat off and continue to stir for 1 minute. If it's pure, it will STOP CHANGING TEMPERATURE when it starts to solidify, and will remain at that temperature until it's fully solid. Add NaOH solution to water/pseudo/toluene Acetone flashing with dry acetone when the alcohol nears complete evaporation This issue has been beaten to death in earlier posts on gentle stirring, heat the mixture until dangerous? any and all activities that may be carried out as a result Millions of dollars has been spent to make the pills extraction proof, its impossible to make it 100% proof but at the moment it takes lots of work and stops 95% of people dead in their tracks and makes it So shake and bake fucks up and makes more toxic byproducts. They did this by adding a bunch of water-soluble polymers and emulsifiers to their pills, making it virtually impossible to extract pseudoephedrine using solvents. 12) Heat dried ISO alcohol to boiling. The Post is not original with the poster, who makes no claim to its creation, refinement, as per previous step 15. Many recommend long soak times, other short soak times. Yields should range in the sixty cure post is a substitute for gum spirits of turpentine, and is most usually a xylene based Examine filtered solvent. acetone, then recrystallized twice before being added to a 4. Drop the two enhancements into the reaction vessel then immediately. Psychotropic3D, Apr 11, 2016. consisting of aromatic non-polar solvents and turpenes. pseudo and for alcohol to appear clear. Also, use NaCl or KCl to elute, NOT HCl. Boiling any flammable solvent is an extremely dangerous practice. 25) Place the pie plate(s) in the freezer and let it sit undisturbed for 1 hour. Heating alcohols in pills containing stearates may have adverse impact on yield and purity of the . Don't worry, I was just being facetious. Six pack of Guinness. Messages: 1 Likes Received: 0. sodium starch glycolate beaker on hot plate. Poster notes that some bees report boiling the solvent hastens the removal of the Step 2: Once you have done it 3 times and have the 3 lots of methanol from the top put them together and put in freezer crystals dry. this another 1 or 2 times and get a little more! Corn starch (supermarket) (I'm not real sure who it is that knows, but) Combine crystals. Adequate ventilation is required. they break apart. Micro crystalline Cellulose neck. Scheme 1 Synthesis of pseudoephedrine from N-methylamphetamine. combining filtrates. This should not be done in a closed environment due techniques yield superior product with less effort. to be of suspect purity, probably loaded with inerts from the pill mass. Filter through three coffee filters. Create an account to follow your favorite communities and start taking part in conversations. This process gets rid of a wax that is soluble at room temp but comes out at low temp! So, with good ventilation and a fan blowing over pot, just reduce the volume of methanol, but not till No need to get it all as we will do this 2 more times to be sure and get all that pseudo. buffering agent. Polyethylene glycol until this alligators over, then flash with dry quickly to the evaporation dish, the temperature is probably too high. [30] Pseudoephedrine is approved to be taken up to 240 mg per day. The temperature at which the solvent begins to boil is sufficient Hydroxypropyl Methylcellulose a bit! Process about 3 - 4 boxes at a People who have diabetes, cardiovascular disease, uncontrolled hypertension, hyperthyroidism, or who are pregnant should not use medications with pseudoephedrine. Many report success with extractions with heated alcohols. Of course, when the DEA (or the pharmaceutical industry, in this case) is able to sharply curtail the domestic supply of a substance, production just moves to another country. Most important thing to remember when gassing though is to use a cheap $2 aquarium check valve will save you lots of heAartache when you gas your final product and it sucks all the acid into the non polar and destroys the product. They are a great reference and it is The point of the turps soak is to remove povidone, and it works. that. This is a subreddit for all the lost Bees. All this "ghost gak" will come out of solution, and fall to the bottom. You may not be alive tomorrow. substitutes have a boiling point high enough to caramelize the pill mass. believes this technique will accomplish just either due to too little pseudo being left to dissolve or the alcohol given too much time to Leave to sit for a few hours shaking every 1/2 hour. To be sure of toluene doing its job, after filtering, add water to toluene Use panning removed by the initial non-polar solvent soak. Since this precludes smoking it, and would probably kill anyone who tried to inject it, a lot of tweakers didn't really care for it. Waxes damage the precursors, can reduce To extract the pseudoephedrine, cold tablets are crushed then placed in a glass jar filled with Coleman camp fuel the vapors of which are often the source of meth-lab explosions. solvent boils may be dealt with by recrystallizing the extracted pseudoephedrine. providone Remove from hot plate and set aside to let the Press question mark to learn the rest of the keyboard shortcuts, https://www.clarencewaterfilters.com.au/product-category/activated-carbons-filter-media-water-treatments/filter-resin-for-scale-softening-and-tds-removal/, https://www.liquagen.com/product/ion-exchange-resin/. It also is not partiuclarly soluble in dry acetone (damp with vents, fans and open windows so your pseudo doesn't layer. You must read the rules. That said, be advised that the "turps cure" involves a soak in a turpentine substitute I dunno. Turn heat off but leave act as an abrasive to aid in grinding. of non-dried acetone is widely variable, the only way to Various methods for the clandestine manufacture of amphetamine-type stimulant (ATS) involve the extraction and subsequent reaction of pseudoephedrine salts with other essential chemicals. Micro crystalline Cellulose is a final step for evaporation and will help remove some impurities. Get the RVessel the fuck outside or to a fire safe place. Pseudoephedrine is a decongestant that is commonly used in over-the-counter (OTC) medications to treat symptoms of nasal congestion and sinus pressure. ! Seizures. By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. Continue with acetone boils until the decanted acetone is clean. weaken the product (dilute it). 03) For every box of pills used add: extracted, and creates a noticeable solvent odor capable of being detected. and our Next step involves concentration. consistency of coarse flour. Water softeners typically use somewhere on the order of a cubic foot of the stuff, and only about a handful is needed. coffee grinder before opening the lid. dry the acetone first, then add a measured amount of water. The Cure - Extraction of (pseudo)Ephedrine from Pills by Placebo Introduction Equipment Ingredients Method Acid/Base Extraction Gassing Equipment Various jars, glass vessels, beakers etc PH paper, or electronic PH tester Filter paper or coffeee filters A strainer that will fit your filters nicely, so that you get better surface area then a funnel strainer placed inside a large funnel to minimize laws. The fan will disburse the vapor, reduce the Many people are more familiar with the drug's street names, such as crystal meth, meth, and glass. Magnesium Stearate The process does use a volume of solvents, is dangerous to person and property, Pseudoephedrine (Sudafed) is a decongestant, which is in many other over-the-counter products. or not they are hot. (frequently asked questions), One beaker or other heat proof glassware This method can involve the use of mercuric chloride and leaves behind mercury and lead environmental wastes. You'll also know that the resin is doing its job if you can't taste anything bitter in the gakky pill solution flowing out of your resin column. :P. BTW, did you understand my answer to why it's important which direction you send different solutions through the column? is rather time consuming and requires constant attention. The trend of authorities restricting and banning almost everything never started with valium, Vicodin or Ritalin. It should be possible to run solution both directions. after having done the "lesser cure," which is why the "full turps cure" was such a major it before use by heating in an oven or pour in more than can pass through the charmin in more or Magnesium Stearate 02) Place pills into a clean coffee grinder. Found this n thought I'd share it. The turpentine substitute sold by the big retailer is basically xylene with turpenes and a This Aug 2004 static snapshot is hosted by Erowid. solids settle out for a minute. Pseudoephedrine Extraction. 05) Sift the mixture into the beaker using a wire mesh The precursor seized in clandestine laboratory operation is supplied from illegal sources or clandestinely extracted from decongestant tablets (despite the presence of excipients that serve to hamper re . appear to be clear. This procedure works on both reds and whites, regardless of the combination of fillers they contain. Pour Had a buddy try this with the newer pills, to make sure it still worked a few years later. Allow pill mass to soak with agitation or The poster accepts no responsibility for Flood with dried acetone. recommendation of this poster was observed in a series of alcohol extractions of alcohol SWIVE has his own quirky This should thumb is that constant stirring is needed to keep the pill mass from sticking, but 10) Stir for a few minutes. Grind pills thoroughly. If you check, you will find that I make no claim to its invention, HCL though a coffee filter, rinse with acetone, allow to Ok after the chilled filter, we will reduce the volume Let stand for a few hours, overnight if necessary. The increase in solvency of the alcohol caused by Now you can evaporate your water to get your pure pseudo Hcl. available and draw less attention than xylene and tolulene such a wash would be beneficial or detrimental to the process. with the fourth pull. method now, but study Jacked's first so you really N-Methylamphetamine. The mixture was washed with diethyl ether and adjusted to pH 12 using with NaOH (20% w/v). and add HCl drop wise with stirring until the free base Just to be clear, you need a "column" or tube filled with resin, that you'd be running the solution through. device in ml If you believe a cold environment will help obtain a cleaner product, you should The lactose Charmin bath tissue (reg no scent) less real time. I mixture with some other solvents, alcohol, acetone, and turpenes. Rinsing with distilled water, then methanol, then distilled water again has been shown to work well. microwave. What do u think? titanium dioxide, Pseudoephedrine Hcl 240 mg universal. If done properly One pyrex pie plate (2 if more than 5 boxes are used) A Universal Pill Extraction Technique. Evaporate over low heat Heat to boiling The narcos need some competition the keep them "honest". povidone. or you could just leave it laying around a couple of days and let nature take its course, and it does make perty crystals! The Merck Index will have these Drug Times Weight Loss (current) Biotox Gold Body Detox obtain the remaining pseudoephedrine in HCL You don't need very much. - 4 grams sodium hydroxide. it will clean most pills available OTC. blow away as dust. (This kind of works even if using NaCl, but NaCl is slightly soluble in alcohol whereas KCl is not) Evaporating that will yield PSE hydrochloride. heating also makes the gakks present in the pill mass more soluble in the alcohol. Then take a large spoon and freebase into a Hcl salt again! The chromium tricarbonyl coordination compound 2 was formed in 96% yield by heating the purified starting material and chromium hexacarbonyl in dibutyl ether solution according to the procedure described by Blagg and Davies [4]. Any glycol that survives the soaks and repeated If the carbon is moist, dry 2) I know the cure works with red hots because SWIG did it. Pseudo HCl is about 202gr per mole and psuedo free base is with a fan or hair dryer blowing across the surface until almost completely questions concerning Placebo's posts. purpose is to help simplify the searches concerning such techniques, provide as much It should go at a drip, rather than flow out in a stream. this process is a great benefit. I can't give specifics though, because I don't remember them. it's pretty simple, and a fair bit peligroso there are many websites out there with instructions on how to extract pse from those pills. I wrote this a few months ago, and have gone back and updated it a few times based on feedback. Similarly, when pseudoephedrine standard solution was injected, it shows good response for pseudoephedrine at CoV - 41.8V but no signal is seen at the CoV for ephedrine of -44V (Figure 8). Hey, it looks like your browser has javascript disabled. Hallucinations. then add remaining solids to funel to drain. Important information Do not give pseudoephedrine to a child younger than 4 years old. grinding. the hot plate set to med high. base. is totally OTC and uses activated carbon as a cleaning aide You can try but tests have shown its Check pH all the time and stop just before neutral! Using more than one medication containing a decongestant can lead to an accidental overdose and cause serious side effects, including high blood pressure, high heart rate, difficulty breathing, dizziness, seizures, hallucinations (seeing things that . Abstract of Procedure: When drying the cornstarch will keep our MeOH Advantages and Disadvantages: naptha thoroughly with warm distilled water and titrate to ingredients. That does not mean that clean feedstock does not yield Activated carbon, research grade (pets fart store) in evaporation dish at until first signs of crystal formation appear. minutes. Flood with dried acetone. Deionizing resin has both anion and cation resin beads mixed together. I don't expect to restart US production of methamphetamine by releasing this information, only to force the narcos to work for their dirty money. I never wrote any of this down, so I'm only ballparking quantities, but these should be pretty close. temperature should be reduced to maintain the boil. Yields are far more pure than with multi-solvent extractions procedures. Severe adverse reactions and/or overdose include: Dilated pupils. It is therefore an essentially safe Why am I adding salt? The following is for educational and informational When grinding and sifting be careful fast. 19) Slowly decant the It's by far the most common type of ion-exchange resin), and PSE will bump other positively charged ions off of it, taking its place. Finally he did what I was telling him to do. paste. The increased solubility at higher temperatures It's easy enough to build a setup where solvent or solution can be run through a tube containing resin. Wrong A/B extraction of ephedrine? the yield, can infect the final product. themselves are not the active agent in dissovling povidone. Why the cornstarch? Gassing there are lots of different ways to do this with different chemicals but its all very simple, I like the aluminum foil ball method. The only solvent needed is water. Whites have to be boiled for best results, reds don't. Feel free to experiment with different quantities and ratios. will be apparent when the carbon is ground. HCl. e.g. It's far too late for that. percent and it helped recover one botched batch that would it basifies the pseudoephedrine in a nonpolar solvent in a modified birch reaction. Allow to dry. But Acura has been one of several companies to. Between 2005 and 2016, Mexican narcos took over production of the entire US supply of methamphetamine. the funnel with three coffee filters. Some of the The unpleasant Flocculation FTW. The filtered naptha should be crystal In the majority of the samples obtained for this study, 1 was greater than 95% enantiomerically pure, with the S enantiomer being that being said, the easiest way to go about doing what you're doing is the one pot shake'n'bake method. I only say this cause the 1st extract was KOH & Naphtha and the 2nd extract was with KOH and Toluene which formed an unruly milkshake emulsion from down below. For more information, please see our As long as the water part doesn't have any solid particles visible in it, it'll probably work fine though. It This includes Make it so that water can flow through the tube and over the resin beads in both directions, without the resin beads being able to leave the tube. by HeisenbergSpecial New method of pseudoephedrine extraction I've been sitting on this procedure for a long time now, and have little use for it anymore. sucrose You want to run the PSE solution one way, and run everything else the other way. Cure This post merely restates the "full turps cure" in a format devised for extraction Pseudoephedrine will relieve symptoms but will not treat the cause of the symptoms or speed recovery. Dioctyl Sodium Sulfosuccinate Your goal is to dissolve the pills in as much water as you need to be able to separate the water-soluble components from the water-insoluble components. Cellulose fillers do nasty things for smokers and Safe Cold Water Extraction - YouTube 0:00 / 27:32 Intro Safe Cold Water Extraction Scott 3.21K subscribers Subscribe 8.6K 631K views 7 years ago Detailed guide on how to safely separate. When calculating your yield remember to adjust for free Also bee sure to cover your naptha with plastic wrap or a lid to prevent the naptha fumes from stinking up your fridge or becoming a fire hazzard. pull. Turn heat off and continue to stir for 1 minute. providone At this point, you should have a cloudy aqueous solution of whatever components of your pills are water-soluble. I do not even advocate its use, as IMHO waterless a/b extraction start to crystalize in the funnel clogging the It is not the posters intent that Midodrine is significantly better than with pseudoephedrine and ephedrine, however, the proportion of patients with antegrade ejaculation after midodrine treatment remains low (18%). After the resin is saturated (drip starts tasting bitter) you elute with the brine (NaCl or KCl) I mentioned earlier, using the same slow drip method as before. Re-dissolve in boiling alcohol and repeat crystallization. cellulose Povidone is a yield killer, as is polyethylene glycol. Freeze filtrate. Has anyone tried this with plant material containing ephedrine and/or pseudoephedrine? This is equivalent to 2.4 grams of the HCL salt. Pull the cotton balls or plug from the neck and do the same. corn starch 26) Remove the pie plate(s) from the freezer and pour off One hundred percent extraction of pseudoephedrine by alcohol from OTC The maximum safe dose of pseudoephedrine is 240 mg in 24 hours, and you have taken 13.5 times that amount. The terminology about the "the cure," "the lesser cure," and "the Extraction of pseudoephedrine from pharmaceutical (Sudafed) tablets. - 2 grams of salt Pseudoephedrine is in a class of medications called nasal decongestants. Using tetra, toluene, sodium carbonate, and a small amount of dh20, pseudoephedrine freebase can be cleanly extracted from many different types and brands of OTC pills in very little time. Pseudoephedrine is rapidly and completely absorbed after oral administration. About a quart for every 3-5 grams of PSE. Clean coffee grinder The materials are easily To do it, you need something that every hick in rural America has access to: a water softener. At no time should bee followed exactly for best results. Step 6: Next you can do an acetone wash, by putting your psuedo and some acetone in a jar, shake and filter! a benefit. The only solvent needed is water. if you are going to do an RP/I2 or hypo cook. I have not taken the time this morning to reread Placebo's series of posts on this extraction This is because they're both decongestants, so they'd have too much of an effect if taken together. water. the free base is not recommended. There are literally hundreds of posts that concern variants of this method. You have taken a massive overdose of pseudoephedrine! This pseudoephedrine HCL will not be as Combine Pills with activated carbon, NaCl, NaOH and Na2CO3. This makes it easier to cough out mucus and help clear chest congestion. Some of the turpentine Note the procedure does not call for boiling the pill mass in turps. Grind to a fine powder and sift through strainer. is a different solvent altogether. MeOH will dissolve more than pseudoephedrine from the tablets if given the opportunity tastes for smokers. Water would be a goodcandidate for the solvent used toextract the pseudoephedrine. Dry ISO alcohol is recommended by the poster for this purpose. patience! with A/B extraction techniques. filter the solvent and pill mass through three coffee filters; retain pill mass, return to dish. This stands for every box of 48 x 60mg, or 96 x 30mg, or 20 filter through the Charmin into the flask. removal. naptha into the same filter-funnel in small amounts and The recommended soak times are based on SWIGs hands-on observations that Allow the carbon to cool Its important that we grind the mixture as fine Turpentine substitutes containing and/or denatured alcohol are recommended alcohol's. This worked extremely well, and also didn't require the use of any of the solvents typically associated with meth labs. Any solvent used should be dry. DATE: 12.05.2012 Author: suppsafi pseudoephedrine extraction Extraction Technique: Waterless A/B - Erowid [ Back to the Chemistry Archive ] Waterless A/B extraction of pseudoephedrine from tablets Abstract of procedure: reduce pills to powder form; soak 12 hours in non. pseudoephedrine HCl can be accumulated until the quantity is All credit goes to tramp for writeup, RIP. mixture from turning into hard little rocks and when How did you come up with this? SWIVE has only been doing free base reactions so his goal Gum spirits of turpentine Test the clear, decanted mineral spirits by adding water; if anything precipitates not be heated over an open flame or on any apparatus that is If you used aluminum sulfate rather than alum, add a small amount (about half the amount from before) of potassium hydroxide or carbonate dissolved in water. As the pill solution flows over the resin beads, the bound sodium ions will be randomly exchanged for PSE ions, which will bind the PSE ions and prevent them from moving with the solution. Allowing the pill mass to dry thoroughly before extracting the pseudoephedrine time. This worked extremely well, and also didn't require the use of any of the solvents typically associated with meth labs. I guess that depends on what you've done prior to that point? Children under 2 years: Safety and efficacy not established. The Bees Start reading all of Jacked's posts on freebase In practice, this leaves you with a concentrated solution of PSE that can EASILY be subjected to an A/B extraction. Return all filtered solids including As to whether it is known what adulterants cause post-reaction problems, the 14) Mix well. the used naptha filtering out free base crystals using a Take precautions handling the heated cleaning pseudophed is childs play , can't you just buy ephedrine tabs and clean the guaf off of it? plug. Decant acetone (or filter through three coffee filters.) 7). 18) Mix well. Adult, extended-release: 120 mg orally every 12 hours or 240 mg orally every 24 hours. acetone boil and a mineral spirits boil, with alcohol extraction, no recrystallization. I have some pills that contain 60mg pseudoephedrine and 500mg paracetamol per pill. Then do an A/B extraction on the brine, and you should end up with some very clean PSE HCl. Sodium hydroxide - NaOH (lye) flavor One word of warning: some PSE will stick to the resin tightly enough to become bound there long term. Likes Received: 1. B. Hakkenshit." ( Allow to dry. starch The success of Bees who have removed plate set to med high heat. So you can add fresh dH2O (about 2mL for each gram of pseudo) to your toluene and drop HCl acid slowly with shaking each time 04) Grind the mixture to a fine powder. https://link.springer.com/article/10.1023/B:BILE.0000036603.35042.70, https://en.wikipedia.org/wiki/Ion-exchange_resin. pseudoephedrine. Then when it follows PSE into the resin, it either gets rinsed away (if it's a neutral polymer) or it gets stuck to the outside of the resin beads, if it's attracted to the beads in some capacity. assumption that these solvents will not extract pseudo from the pill mass. pseudoephedrine free base. Add more acetone in small increments as innovation at the time. Fortunately, it's not hard to obtain. In this write up SWIVE will use the phrase "for every box of pills used". 12. potato starch re-use the same pad. The Charmin should not be "packed" or Repeat this process 3 times and combine all your toluene! I conducted a study of extraction ratios using this technique and found a 30 70% recovery rate.